AdverseEvents: Why Big Pharma Is Scared Of This Startup

RA Guy Community News 5 Comments

By taking lists of potential side effects out of the hands of the drug makers, the startup is letting people know what their pills might be doing to them in a more open way than big pharmaceutical companies ever have.

AdverseEvents, a California-based startup, is pushing the debate out into the open with a centralized database of how many side effects are happening from what drugs and what the patient outcomes are–and according to cofounder Brian Overstreet, “it scares the crap out of the pharmaceutical companies.”

“The FDA has some of this [side effect] data, but it’s unstructured, not searchable, and not standardized,” explains Overstreet. AdverseEvent’s proprietary algorithm, which took 18 months to build, takes into account data from the FDA, direct patient reporting, and even information from social media sites (AdverseEvents analysts are alerted to side effect discussions on patient discussion boards, for example, and try to extract data).

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AdverseEvents, Inc. (AEI) is the first service provider to deliver accurate, real-time information on adverse drug events reported to the FDA. AEI utilizes a unique data sourcing method called RxFilter™, a proprietary 17-step data refinement process that standardizes and normalizes the data from the FDA’s Adverse Event Reporting System (AERS) into a user-friendly, fully searchable, database of over 4,000 approved medications.

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Comments 5

  1. Post
    RA Guy

    The #1 condition with highest number of adverse drug events reported: Rheumatoid Arthritis.

    The #1 drug with highest number of adverse drug events reported:

  2. Frank

    I must be a lucky guy, I have been using Enbrel for nearly two years and have had no adverse reactions. I am so happy not to be in the kind of pain I had before it. When I was using Celebrex I broke out with small red spots just around my chest and back.

  3. Deb aka murphthesurf

    What a great resource for us! What I didn’t see was the total number of patients that have used a medication. 40K of adverse reports for a medication may appear high but one needs the total number of patients that have used a medication to get a percentage. What I found fascinating was the deaths. That was scary indeed!

  4. Murfomurf

    Great- I’m so glad the AdverseEvents has started up. I think someone should start one in Australia (or a branch of the California one). It’s wellnigh impossible to get true frequencies of drug-related adverse events in Oz- I’ve been trying to do some research for years. It first started when I explored some hospital admissions data I was given for another purpose (BADD ME) because I had experienced a really wet chest while on Vioxx for tennis elbow. As I don’t ever get a bad chest except with a cold etc, I decided to see if the symptoms had been reported more on hospital admissions since the introduction of Vioxx to the local government pharmaceutical schedule. I looked up any ICD codes I could think of where excess fluid on the chest occurred NOT due to a respiratory admission. Lots of “heart failure”- associated cases came up. Sure enough there was steady rise in these cases parallel with the number of scripts for Vioxx. I’ve tried to get figures from the TGA here, but they send all their data to the international db in Helsinki & force yoou to pay for access (bummer for Masters’ students like me). The local hospital incidents db is quite good for the last few years, but the drug side effects are only selectively recorded according to nurse observations. I’ve been held up for more than 12 months trying to get access to state health data I have been approved to view & use for my dissertation (nominally a 6mth program) & have become quite depressed- which could easily be cured by a local AdverseEvents branch!

  5. Scarletkate

    Thank you so very much. I am starting on Cimzia a week from today and I was grateful to be able to go to the website and check it out. I was feeling pretty apprehensive about starting it, but it seems to be among the safest of the biologics listed.
    Thanks again 🙂

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